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楼主: 东方

求:特罗凯耐药后的治疗方案!!(妈妈2007年12月4日病逝!)

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发表于 2007-7-19 13:24:50 | 显示全部楼层 来自: 美国

我最近一直在网上搜索DCA的材料,有关肺癌的结果并不太乐观,但是好消息是,加拿大多伦多的一个癌症治疗中心最近开始正式用DCA进行试药,估计很快就会有结果了。下面是有关的链接

7RScr3p01YJ:www.medicorcancer.com/DCAtherapy.html+DCA+lung+cancer&hl=en&ct=clnk&cd=40&gl=us">http://64.233.167.104/search?q=cache7RScr3p01YJ:www.medicorcancer.com/DCAtherapy.html+DCA+lung+cancer&hl=en&ct=clnk&cd=40&gl=us

癌症治疗中心的名字是 Medicor Cancer Centers.

We are accepting patients for DCA therapy.

Due to the large number of inquiries about DCA we will be updating this page regularly with our latest information.

DCA (dichloroacetate) is a drug that was recently found to rapidly shrink human breast, lung and brain cancer cells that were implanted into rats, while being non-toxic to healthy cells. This research was published in Cancer Cell, 11, 37–51, January 2007. DCA has been found to kill cancer cells by a newly discovered mechanism that appears to be common to several types of cancer. No formal research has yet been done to determine if it will work on cancer within the human body.

Medicor Cancer Centres is the first cancer clinic in Canada to begin prescribing DCA to cancer patients under the full supervision of a medical team. We have made Federal and Provincial regulatory bodies (including Health Canada, the College of Physicians and Surgeons of Ontario and Ontario College of Pharmacists) aware of our DCA therapy practices and we are abiding by their relevant guidelines and policies.

We would like to acknowledge and extend a special thanks to two of our patients who brought DCA to our attention, and motivated us to begin DCA treatments.

Is DCA safe?

DCA has been used in humans to treat a rare disease called “congenital lactic acidosis”, and found to have some mild to moderate side effects. Although DCA is likely safe to use in cancer patients, we don’t yet know for sure. Our limited treatment experience to date suggests that DCA can be safely used by cancer patients under close medical supervision.

DCA can cause temporary nerve injury in the hands and feet. This is preventable, and treatable if it occurs. There may be other mild to moderate side effects such as fatigue or nausea, and we have noticed confusion and memory problems with higher doses in several patients.

Some animal studies show that DCA can itself cause liver cancer. These studies used doses which are over 1000 times higher than what would be prescribed for cancer treatment.

All Medicor patients who receive DCA will be closely monitored by our physicians for drug side effects with routine check-ups, comprehensive lab tests, and imaging studies. We take into account our patients’ general condition, other medications, past medical history, and concurrent health problems.

What have Medicor patients experienced so far?

We have treated patients with the following cancers with DCA so far:

  • non-small cell carcinoma, lung
  • adenocarcinoma, colon
  • mesothelioma
  • small cell carcinoma, primary unknown
  • breast carcinoma
  • adenocarcinoma, prostate
  • squamous cell carcinoma, oropharyngeal
  • adenocarcinoma, pancreas
  • cervical carcinoma

Most of these patients have been told by their oncologists that there are no other treatments available for them.

It will take many months of treatment of many patients for us to determine how effective DCA is. We are seeing some positive responses to DCA including tumour shrinkage, and improvement in lab tests, but it is still too early to say how successful DCA treatments will be. Most side effects reported so far have been mild or moderate, and some patients have stopped DCA because of them. Common side effects include, heartburn, nausea, numbness/tingling in the hands or feet, confusion, memory loss and hand tremor. Side effects are either treated with medication, or the DCA dose is adjusted.

We are constantly evaluating the benefits and side effects of DCA, and are using this data to adjust and improve our treatment protocol for maximum patient benefit and safety.

Isn’t it better to wait for a DCA clinical trial?

Medicor believes that is essential for clinical trials to be conducted to prove how well DCA works as a cancer treatment. DCA is different than other “new” drugs, because it has already been used for decades in humans, and has a relatively safe profile. This means that the clinical trials will take less time, but it can still take years. Many cancer patients cannot wait this length of time.

Also, we are aware of many patients who are currently self-medicating with DCA, or are being treated with DCA under naturopathic care alone. In order to assist cancer patients to receive DCA treatment in the safest possible way, we are offering DCA “off label” as a cancer treatment under full medical supervision.

We respect the patient’s right to choose their treatment once they know all the potential risks and benefits. All of our DCA patients understand that DCA is not yet scientifically proven as a cancer treatment.

We are hopeful that information obtained from our experiences with DCA will supplement clinical trials, and help patients and the medical community.

Is it available?

Yes. We obtain certified pharmaceutical grade DCA from a reputable multi-national chemical company for our patients. Our DCA is manufactured under strict regulations in USA. We have clearance from all the relevant Federal and Provincial regulatory bodies to obtain and dispense DCA. It is compounded into capsules for us by a licensed pharmacist, and usually dispensed from our pharmacy to our patients biweekly. DCA can only be dispensed to patients who come under the care of our physicians. DCA patients are not required to subscribe to our private care services.

What is the cost?

The cost of DCA treatment at Medicor is about $150 per week depending on the dose. During the course of treatment, all medically-necessary doctor’s visits, blood tests and imaging are provided/arranged at no cost, provided you have a valid Health Card from Ontario, or any province (except Quebec).

We will advise you when you begin treatment if there are any supplements that are recommended. These are available over-the-counter at most pharmacies.

What is the duration of treatment?

In order to determine if DCA is effective in treating your cancer, we recommend at least one month of treatment. If your cancer responds to the drug, therapy may continue indefinitely. If you experience significant side effects, treatment will be stopped and may be restarted later.

How do I become a Medicor DCA patient?

We are accepting patients with a documented diagnosis of cancer (any type) preferably who have:
a) failed conventional, scientifically proven treatments, or
b) been told by their doctor that there is no effective treatment for their cancer.

For patients who wish to combine DCA with conventional therapy such as chemo, or to take DCA instead of conventional therapy, we do not generally recommend it. However, if you still wish to pursue some of the latest cancer treatments, please contact us. We support the patient’s right to make an informed decision about their own care.

Please obtain your Pathology Report (confirming the diagnosis of cancer) immediately if you wish to receive DCA. If you do not have a Pathology Report (you did not have a biopsy), we require your specialist’s notes confirming the diagnosis of cancer. If you are unable to access these documents, please call us for assistance.

A valid Health Card from Ontario or any province (except Quebec) is required. Patients are only required to pay for the medication, as it is not covered by Ontario Drug Benefits. For patients without a valid Health Card, please contact us to discuss treatment costs.

Please note that the Ontario College of Pharmacists requires the use of pharmaceutical grade DCA. Therefore, we are presently treating patients using our own verified source of compounded pharmaceutical grade DCA capsules. Patients wishing to bring their own DCA regrettably cannot be treated.

You can call us at (416) 227-0037 or email us at info@medicorcancer.com to make an appointment to discuss your individual case.

有爱,就有奇迹!
 楼主| 发表于 2007-7-20 14:02:49 | 显示全部楼层 来自: 中国广东深圳

感谢jimmy的热心支持!

TO 小路和大家:

对DCA的使用到现在为止也仅止于一些机构的实验报告及民间使用情况反馈,具体的疗效,我们也无法从中一一考研,但有一点我们可以肯定的是DCA对癌症的治疗是有作用的,我们不能期待这种作用能够替代目前的标准治疗用药,但当化疗和靶向药物都无效的情况下,我们的选择还有什么?!我没有期望DCA给带来奇迹,但至少有一点,哪怕有一点点的希望,我都决不会放弃!

有爱,就有奇迹!
 楼主| 发表于 2007-7-20 14:06:40 | 显示全部楼层 来自: 中国广东深圳
7月19号,是妈妈服用DCA的第6天,白天的反应情况还不错,但到了下午5点半后,妈妈突然一阵剧烈咳嗽,感觉到由于胸积水和左肺目前肿瘤很大压迫气管原因,她是有痰咳不出来,所以人显得比较辛苦,晚饭也吃得较少。晚上在床上躺着休息,也没精神看电视了。直到晚上10点半刷牙睡觉时,又咳嗽一阵,腰部疼痛,给她吃了一粒西乐葆止痛。体温方面,晚上7点测得37.2度,有些低烧,到睡前,体温逐渐恢复正常。
[此贴子已经被作者于2007-7-20 14:10:08编辑过]
有爱,就有奇迹!
发表于 2007-7-21 06:53:40 | 显示全部楼层 来自: 中国上海
谢谢东方、jimmy。明天是星期天,去国际礼拜教堂,为大家祷告!
有爱,就有奇迹!
 楼主| 发表于 2007-7-21 08:58:13 | 显示全部楼层 来自: 中国广东深圳

7月20号,是妈妈开始服用DCA后的第7天。早上,妈妈起来后感觉一般,主要还是想咳嗽和咳不出痰的原因所以整个人精神不太好。决定减量服用,10mg/kg/day的量用一天。下午的情况比较好,一直都有精神看电视。但晚饭胃口不好,就喝了碗汤和稀饭,7点钟测体温37.5度,到8点半再测体温是37.1度,有所下降。观察妈妈今天的情况,觉得咳嗽和反胃是两个比较突出的现象,今天打算针对这两方面进行用药。

另外,请教大家,有止咳去痰方面较有效的药可以介绍吗? 对于去痰药用了沐舒坦和喷雾效果都不太好,暂时想不到有什么好的药物了[em06]

有爱,就有奇迹!
发表于 2007-7-21 15:47:59 | 显示全部楼层 来自: 中国广东深圳
东方:我附近有个中医看咳嗽很有办法,我妻子凡咳嗽都找他,效果不错。如有需要打我电话或发邮件给我。
      
有爱,就有奇迹!
 楼主| 发表于 2007-7-22 15:37:10 | 显示全部楼层 来自: 中国广东深圳

谢谢哈里,妈妈这两天咳嗽好象开始好转,痰也较少了,不知是否DCA开始起作用了,感觉上应该是有作用的。

我应该有你电话,有需要会给你电话,谢谢。另外,你妻子最近情况怎么样了?

有爱,就有奇迹!
 楼主| 发表于 2007-7-22 15:44:31 | 显示全部楼层 来自: 中国广东深圳
7月20日,妈妈上午测得体温37度,人虽然感觉有些疲倦,总体还算可以。由于昨晚吃了开胃药(梅格施),中午吃饭胃口不错。决定今天的DCA用量还是按15mg/kg/day使用,午饭、晚饭后一小时服用。下午体温降下来了,咳嗽明显减少,疲倦感比前几天有较大改善,期望中的DCA药效可能正在起作用![em01]
有爱,就有奇迹!
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