易瑞沙耐药后的解决方案，请大家都来找出路

iamsharuru · 发表于 2008-5-14 10:36:30

jimmy能给我一下联系方式吗？我想问一些关于去美国接受治疗的信息

junjun123 · 发表于 2008-5-14 20:49:15

建病例+治疗方案)+顺便请教问题<div style="MARGIN-TOP: 10px; FONT-SIZE: 9pt; MIN-HEIGHT: 200px; WORD-BREAK: break-all; TEXT-INDENT: 24px; LINE-HEIGHT: normal; WORD-WRAP: break-word;">病例：我妈妈今年53岁，还是中青年。确诊前的症状为咳嗽（并不重），全身无力，无胃口。因为跟我爸爸吵架赌气去检查发现左肺部有阴影。  去年11月底在潘家园肿瘤医院确诊为：左肺腺ca, Iv期，纵隔，淋巴，转移，多发骨转移。轻度脂肪肝。治疗：去年12鲁跞胱”本┢障橹幸街琢鲆皆骸＝邮苤幸街瘟啤?为期两个月，治疗如下：消癌平（乌骨藤提取液）+中药中药初期为医院熬煮，后一个月是我自己煮。自己煮的药方比较大，分甲乙两个方，煮好了，两个要一起喝。期间做肿标检测，（因为是非小，腺，所以以CEA为主） 第一个月的肿标比入院前增长11个，第二个月下降20，医生和我一致认为病情遭到控制，于是回我家继续大剂量中药治疗。出院后的治疗：大剂量中药+金龙胶囊+云南白药外敷药治疗骨转移状况我妈妈状况一直还可以，胃口也不错，行动自如，每天锻炼3次，做些轻微的家务。骨转病灶并不是很痛。——————————————————————————————————————————————————问题1.因为服用了5个多月的中药，脾胃功能很不好，晚上吃多了会胃胀，经常胃酸。中途出现过一次胃出血。 2. 4，5两个月的CEA(每个月都在测)上升了。医生（中医）认为可能是病灶发展了。建议做综合检查。我正在预约中。。。今天医生有了新的治疗方案，如下：易瑞沙+小药方（指调理脾胃，提升正气为主的药劲儿比较小的药方）2个月然后大药方（指抗肿瘤功效比较大的中药，劲儿比较大）两个月如此交替使用。请大家帮我分析一下，这样易瑞沙跟中药交替使用，可行吗？我现在比较懵，请大家帮忙指导我一下。</div>

jimmy112199 · 发表于 2008-5-15 08:50:55

iamsharuru: jimmyshu2001@yahoo.com 如果没有身份和医保，美国治疗费用很高，不值得，但如果是 IRESSA耐药，目前有几个试药，可以试试。如XL184 A Study of XL184 With or Without Erlotinib in Adults With Non-Small Cell Lung Cancer

[此贴子已经被作者于2008-5-15 8:52:46编辑过]

joss · 发表于 2008-5-19 16:02:12

什么叫耐药?????????????????

taoxk · 发表于 2008-5-24 13:48:14

女，38岁，腺癌IV期脑单转移确诊2年，4次化疗并行头部X刀+全脑放疗后服用易瑞沙22个月，病情稳定，生活质量较好。近日发现头部单一新病灶（0.6x0.5cm），医生建议观察一段时间再定是否耐药，如是则考虑重新化疗或改用特罗凯。请问论坛中有没有类似的经验可以参考，或给些宝贵建议，多谢了。

jli999 · 发表于 2008-5-25 03:16:59

<div class="msgheader">QUOTE:</div><div class="msgborder">以下是引用taoxk在2008-5-24 13:48:14的发言： 女，38岁，腺癌IV期脑单转移确诊2年，4次化疗并行头部X刀+全脑放疗后服用易瑞沙22个月，病情稳定，生活质量较好。近日发现头部单一新病灶（0.6x0.5cm），医生建议观察一段时间再定是否耐药，如是则考虑重新化疗或改用特罗凯。请问论坛中有没有类似的经验可以参考，或给些宝贵建议，多谢了。</div>      做了CT检查吗？如果原发病灶没有进展，病人自我状态也不错，可以继续吃易瑞沙，同时考虑对脑部出现的单一病灶做伽玛刀治疗。

[此贴子已经被作者于2008-5-25 3:30:23编辑过]

taoxk · 发表于 2008-5-25 07:16:22

<span style="FONT-SIZE: 10.5pt; FONT-FAMILY: 宋体; mso-ascii-font-family: "Times New Roman"; mso-bidi-font-size: 12.0pt; mso-hansi-font-family: "Times New Roman"; mso-bidi-font-family: "Times New Roman"; mso-font-kerning: 1.0pt; mso-ansi-language: EN-US; mso-fareast-language: ZH-CN; mso-bidi-language: AR-SA;">jli999：<span style="FONT-SIZE: 10.5pt; FONT-FAMILY: 宋体; mso-ascii-font-family: "Times New Roman"; mso-bidi-font-size: 12.0pt; mso-hansi-font-family: "Times New Roman"; mso-bidi-font-family: "Times New Roman"; mso-font-kerning: 1.0pt; mso-ansi-language: EN-US; mso-fareast-language: ZH-CN; mso-bidi-language: AR-SA;"><span style="FONT-SIZE: 10.5pt; FONT-FAMILY: 宋体; mso-ascii-font-family: 'Times New Roman'; mso-bidi-font-size: 12.0pt; mso-hansi-font-family: 'Times New Roman'; mso-bidi-font-family: 'Times New Roman'; mso-font-kerning: 1.0pt; mso-ansi-language: EN-US; mso-fareast-language: ZH-CN; mso-bidi-language: AR-SA;">CT显示肺部原发病灶和转移灶稳定，病人感觉尚可，但这次复查的肿瘤标志物有进展。头晕、眼花、恶心等脑部症状一直不同程度地存在，考虑到她曾经做过头部放疗也没特别在意，最近两次MRI间隔5个月。<span style="FONT-SIZE: 10.5pt; FONT-FAMILY: 宋体; mso-ascii-font-family: "Times New Roman"; mso-bidi-font-size: 12.0pt; mso-hansi-font-family: "Times New Roman"; mso-bidi-font-family: "Times New Roman"; mso-font-kerning: 1.0pt; mso-ansi-language: EN-US; mso-fareast-language: ZH-CN; mso-bidi-language: AR-SA;"><span style="FONT-SIZE: 10.5pt; FONT-FAMILY: 宋体; mso-ascii-font-family: 'Times New Roman'; mso-bidi-font-size: 12.0pt; mso-hansi-font-family: 'Times New Roman'; mso-bidi-font-family: 'Times New Roman'; mso-font-kerning: 1.0pt; mso-ansi-language: EN-US; mso-fareast-language: ZH-CN; mso-bidi-language: AR-SA;">放疗结束时全脑剂量<span lang="EN-US" style="FONT-SIZE: 10.5pt; FONT-FAMILY: "Times New Roman"; mso-bidi-font-size: 12.0pt; mso-font-kerning: 1.0pt; mso-ansi-language: EN-US; mso-fareast-language: ZH-CN; mso-bidi-language: AR-SA; mso-fareast-font-family: 宋体;">28Gy/14<span style="FONT-SIZE: 10.5pt; FONT-FAMILY: 宋体; mso-ascii-font-family: "Times New Roman"; mso-bidi-font-size: 12.0pt; mso-hansi-font-family: "Times New Roman"; mso-bidi-font-family: "Times New Roman"; mso-font-kerning: 1.0pt; mso-ansi-language: EN-US; mso-fareast-language: ZH-CN; mso-bidi-language: AR-SA;">次，局部<span lang="EN-US" style="FONT-SIZE: 10.5pt; FONT-FAMILY: "Times New Roman"; mso-bidi-font-size: 12.0pt; mso-font-kerning: 1.0pt; mso-ansi-language: EN-US; mso-fareast-language: ZH-CN; mso-bidi-language: AR-SA; mso-fareast-font-family: 宋体;">X<span style="FONT-SIZE: 10.5pt; FONT-FAMILY: 宋体; mso-ascii-font-family: "Times New Roman"; mso-bidi-font-size: 12.0pt; mso-hansi-font-family: "Times New Roman"; mso-bidi-font-family: "Times New Roman"; mso-font-kerning: 1.0pt; mso-ansi-language: EN-US; mso-fareast-language: ZH-CN; mso-bidi-language: AR-SA;">刀<span lang="EN-US" style="FONT-SIZE: 10.5pt; FONT-FAMILY: "Times New Roman"; mso-bidi-font-size: 12.0pt; mso-font-kerning: 1.0pt; mso-ansi-language: EN-US; mso-fareast-language: ZH-CN; mso-bidi-language: AR-SA; mso-fareast-font-family: 宋体;">16Gy/7<span style="FONT-SIZE: 10.5pt; FONT-FAMILY: 宋体; mso-ascii-font-family: "Times New Roman"; mso-bidi-font-size: 12.0pt; mso-hansi-font-family: "Times New Roman"; mso-bidi-font-family: "Times New Roman"; mso-font-kerning: 1.0pt; mso-ansi-language: EN-US; mso-fareast-language: ZH-CN; mso-bidi-language: AR-SA;">次，这种剂量还能再做脑部放疗吗？比如伽玛刀、X刀、Cyberknife等。<span style="FONT-SIZE: 10.5pt; FONT-FAMILY: 宋体; mso-ascii-font-family: "Times New Roman"; mso-bidi-font-size: 12.0pt; mso-hansi-font-family: "Times New Roman"; mso-bidi-font-family: "Times New Roman"; mso-font-kerning: 1.0pt; mso-ansi-language: EN-US; mso-fareast-language: ZH-CN; mso-bidi-language: AR-SA;">谢谢您的答复！

jli999 · 发表于 2008-5-25 10:12:44

<div class="msgheader">QUOTE:</div><div class="msgborder">以下是引用taoxk在2008-5-25 7:16:22的发言： <span style="FONT-SIZE: 10.5pt; FONT-FAMILY: 宋体; mso-ascii-font-family: "Times New Roman"; mso-bidi-font-size: 12.0pt; mso-hansi-font-family: "Times New Roman"; mso-bidi-font-family: "Times New Roman"; mso-font-kerning: 1.0pt; mso-ansi-language: EN-US; mso-fareast-language: ZH-CN; mso-bidi-language: AR-SA;">jli999：<span style="FONT-SIZE: 10.5pt; FONT-FAMILY: 宋体; mso-ascii-font-family: "Times New Roman"; mso-bidi-font-size: 12.0pt; mso-hansi-font-family: "Times New Roman"; mso-bidi-font-family: "Times New Roman"; mso-font-kerning: 1.0pt; mso-ansi-language: EN-US; mso-fareast-language: ZH-CN; mso-bidi-language: AR-SA;"><span style="FONT-SIZE: 10.5pt; FONT-FAMILY: 宋体; mso-ascii-font-family: 'Times New Roman'; mso-bidi-font-size: 12.0pt; mso-hansi-font-family: 'Times New Roman'; mso-bidi-font-family: 'Times New Roman'; mso-font-kerning: 1.0pt; mso-ansi-language: EN-US; mso-fareast-language: ZH-CN; mso-bidi-language: AR-SA;">CT显示肺部原发病灶和转移灶稳定，病人感觉尚可，但这次复查的肿瘤标志物有进展。头晕、眼花、恶心等脑部症状一直不同程度地存在，考虑到她曾经做过头部放疗也没特别在意，最近两次MRI间隔5个月。<span style="FONT-SIZE: 10.5pt; FONT-FAMILY: 宋体; mso-ascii-font-family: "Times New Roman"; mso-bidi-font-size: 12.0pt; mso-hansi-font-family: "Times New Roman"; mso-bidi-font-family: "Times New Roman"; mso-font-kerning: 1.0pt; mso-ansi-language: EN-US; mso-fareast-language: ZH-CN; mso-bidi-language: AR-SA;"><span style="FONT-SIZE: 10.5pt; FONT-FAMILY: 宋体; mso-ascii-font-family: 'Times New Roman'; mso-bidi-font-size: 12.0pt; mso-hansi-font-family: 'Times New Roman'; mso-bidi-font-family: 'Times New Roman'; mso-font-kerning: 1.0pt; mso-ansi-language: EN-US; mso-fareast-language: ZH-CN; mso-bidi-language: AR-SA;">放疗结束时全脑剂量<span lang="EN-US" style="FONT-SIZE: 10.5pt; FONT-FAMILY: "Times New Roman"; mso-bidi-font-size: 12.0pt; mso-font-kerning: 1.0pt; mso-ansi-language: EN-US; mso-fareast-language: ZH-CN; mso-bidi-language: AR-SA; mso-fareast-font-family: 宋体;">28Gy/14<span style="FONT-SIZE: 10.5pt; FONT-FAMILY: 宋体; mso-ascii-font-family: "Times New Roman"; mso-bidi-font-size: 12.0pt; mso-hansi-font-family: "Times New Roman"; mso-bidi-font-family: "Times New Roman"; mso-font-kerning: 1.0pt; mso-ansi-language: EN-US; mso-fareast-language: ZH-CN; mso-bidi-language: AR-SA;">次，局部<span lang="EN-US" style="FONT-SIZE: 10.5pt; FONT-FAMILY: "Times New Roman"; mso-bidi-font-size: 12.0pt; mso-font-kerning: 1.0pt; mso-ansi-language: EN-US; mso-fareast-language: ZH-CN; mso-bidi-language: AR-SA; mso-fareast-font-family: 宋体;">X<span style="FONT-SIZE: 10.5pt; FONT-FAMILY: 宋体; mso-ascii-font-family: "Times New Roman"; mso-bidi-font-size: 12.0pt; mso-hansi-font-family: "Times New Roman"; mso-bidi-font-family: "Times New Roman"; mso-font-kerning: 1.0pt; mso-ansi-language: EN-US; mso-fareast-language: ZH-CN; mso-bidi-language: AR-SA;">刀<span lang="EN-US" style="FONT-SIZE: 10.5pt; FONT-FAMILY: "Times New Roman"; mso-bidi-font-size: 12.0pt; mso-font-kerning: 1.0pt; mso-ansi-language: EN-US; mso-fareast-language: ZH-CN; mso-bidi-language: AR-SA; mso-fareast-font-family: 宋体;">16Gy/7<span style="FONT-SIZE: 10.5pt; FONT-FAMILY: 宋体; mso-ascii-font-family: "Times New Roman"; mso-bidi-font-size: 12.0pt; mso-hansi-font-family: "Times New Roman"; mso-bidi-font-family: "Times New Roman"; mso-font-kerning: 1.0pt; mso-ansi-language: EN-US; mso-fareast-language: ZH-CN; mso-bidi-language: AR-SA;">次，这种剂量还能再做脑部放疗吗？比如伽玛刀、X刀、Cyberknife等。<span style="FONT-SIZE: 10.5pt; FONT-FAMILY: 宋体; mso-ascii-font-family: "Times New Roman"; mso-bidi-font-size: 12.0pt; mso-hansi-font-family: "Times New Roman"; mso-bidi-font-family: "Times New Roman"; mso-font-kerning: 1.0pt; mso-ansi-language: EN-US; mso-fareast-language: ZH-CN; mso-bidi-language: AR-SA;">谢谢您的答复！</div>     不能再做全脑放疗了，但可以做伽玛刀等治疗。你再看看病友无香的帖子，她前段时间为父亲的脑转治疗做了很多研究：。<a href="http://www.51qiji.com/dispbbs.asp?boardID=5&ID=610&page=1">http://www.51qiji.com/dispbbs.asp?boardID=5&ID=610&page=1</a>

[此贴子已经被作者于2008-5-25 10:17:40编辑过]

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易瑞沙 耐药后的解决方案，请大家都来找出路

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易瑞沙耐药后的解决方案，请大家都来找出路