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发表于 2009-7-24 23:18:06
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来自: 中国江苏南京
我在论坛中发现了有一个专栏讲述VC的,看来我就不用开新贴了。我就在你的帖子里回复吧。
我前几天给一位加拿大的学者专门写信咨询静滴VC的治疗问题,我把信贴出来供大家参考。这位学者是研究静滴VC治疗癌症的专家,国内翻译过来的相关的前沿文献很多都有他的贡献。国内这方面的进展太慢,只能看国外的文献和报告了。不能等啊,临床试验都很漫长的。
他的回信,之后是我的去信
Thank you for your question.
It appears to me that some cases of renal cell cancer have regressed after intravenous vitamin C therapy alone. However, these cases may represent a small percentage of people treated. Single cases are very important in demonstrating a biological phenomenon, but they are not sufficient to introduce a general therapy.
In our recent relatively small clinical trial, we searched for an effect of iv vitamin C as sole therapy in people who had previously failed all other treatments. We did not find evidence of harm, but neither of benefit. Only 6 people received the highest dose, however.
My research goal is to find out in what way very high concentrations of vitamin C in the body can have anti-cancer effects. In the interests of efficiency, it does not seem useful to my research or to patients with cancer to simply continue giving vitamin C as only therapy. It is possible that some patients could indeed respond, but there is no way to know this, and the percentage of people who respond could be so small is to make the treatment impractical.
We are proceeding to try to test the combination of ivtamin C together with chemotherapy. THere are some reasons to expect the combination might be better than chemo alone. This is a research question, not a standard therapy. Cllinical reseach is slow and tedious, and often discouraging. It takes a lot of persistence. No doubt this is the reason so few good studies have been done.
The main goal of my research is to discover the underlying biological process. In what manner could vitamin C have anticancer effects? Mark Levine at the NIH has been doing important reserach to elucidate possible mechanisms. Once it is understood (if indeed vitamin C does show these effects consistently), then we would be in the position to determine which patients, with which cancers, with which other agents, could benefit from this treatment.
There are people using intrtavenous vitamin C in S. Korea and in Japan. I am not in contact with them, however,
I hope your mother does well.
Yours sincerely,
以下是我的去信
Dear Dr XXX
I am very appreciated if you could read my email. Several months ago my mother got the Renal Cell Cancer. Soon, I began to be strongly absorbed by the effect of Vitamin C on Cancer. I have read your paper "
Intravenously administered vitamin C as cancer therapy:Three cases", which gave me very much hope. But when I read your latest paper "Phase I clinical trial of i.v. ascorbic acid in advanced malignancy", which said "High-dose i.v. ascorbic acid was well tolerated but failed to demonstrate anticancer activity when administered to patients with previously treated advanced malignancies", which seems to indicate negative information on Vitamin C. Dear Doctor, would you please tell me that whether it is the final conclusion? Are you doing the Phase II clinical trials or something else? I have read so many positive and negative things about VC, but not many people but you do the clinical trials, your work are very very important to the people. I am really looking forward to your further research development. Thank you very much!
Best Regards! |
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