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发表于 2010-10-18 12:54:40
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来自： 美国
her interpretation about 经络。 Found another guy called 张明。 This guy got many blogs, and sounds like very confident about treating cancer with Chinese medicine. Yet, no hard truth or anything support that he is a good one. Read more, and then realize what he claimed in his blogs that he got all these recipes to treat cancer are mostly copied from Chinese academy of traditional medicine (Yu guiqing, maybe Piao bingkui as well). Starting to think about synthesize pre-clinical drugs as last resort. Evening, called SHR. He will be on business trip and be back on Monday. Will take my father to in-patient, and do CT guided biopsy. SHR mentioned that the hospital president is number one in the country for lung cancer surgery. If it can be surgically removed, we should do surgery. Called Joy to organize sample shipment to the states. UPS and FEDEX may not work. Joy remind that I may need OCT embed frozen tissue. Also potential concern about biopsy induced metastasis. There might also be custom issues. Didn’t reach HXH. Father and Mother went to see 陈津生(Chinese medicine) today, plus another 游医。.
2010/10/14 Thurs.
Morning, HXH replied. Will call in the evening. Bump into LG, asked her whether there is any clinical evidence for biopsy induced mets. She said there were always concerns, but so far no evidence that this really happens. She was pretty caring and asked about the situation. One point I got from her is that if you are stage 3, particulary IIIa, and you can get surgery done, plus chemo, there is definitive data for 20% 5 year survival. She also recommended Chemo at least if it’s not suitable for surgery. Most importantly, she suggested small operation to take mediastinal nodes instead of CT guided primary biopsy, because it could tell you the situation of mets, therefore better diagnosis (for surgery). Agree with this point. Will discuss with SHR and HXH on Monday.
Day time: Start to research more on Chinese medicine treatment. Came across 倪海夏， and suddenly recalled the debate between 经方and 温病。Start to read more, and decide to look for 经方doctors. 黄煌in Nanjing, 冯佩纶in Beijing and 孔乐凯in Jinan become top candidates. Asked Alexis for the person who did ALK FISH, then emailed Masahiko asking for whether I need OCT frozen tissue for FISH, as PAJ said.
Night: Called ZY about technical detail to synthesize drugs by ourselves. The answer is positive. It is perfectly doable from technical point of view. Called HXH. He said that their president is very good, also mentioned a few people that I knew who got lung cancer and were operated by him are all doing well. Talked about which department should my father get in. Since we don’t know if SHR already organized it, we’ll see on Monday. Also confirmed with him that he has liquid nitrogen in the lab. He reminded about potential custom issues for biosample export. Called Joy, she said FEDEX can ship the sample, but not sure about custom issue. While calling, Masahiko replied email, saying that I only need parafine sections. This is great news. Much easier to prepare and transport the samples. Joy mentioned very important info on drug synthesis. She said that somebody in china already synthesized WZ4002 (at tens of kilos) and already started to give patient secretly. Start to read倪海夏’s 人纪针灸教程。
2010/10/15 Fri. Morning and daytime: busy with work. WKK called, saying that JE offered to work on my father’s samples if PAJ didn’t offer to help. Good to know another back up.
Night: read more Chinese medicine books. Start to form working flow about how to treat my father using Chinese medicine. 针灸按摩以通经络，中药扶正祛邪以安脏腑。Tell my father that he needs to work out. Reason, cancer needs lots of nutrition, and blood flow is providing that. If one move around, blood will go to arms and legs, and if you sit right there or lie down, blood will go where needs it—the tumor.
2010/10/16 Sat. Daytime: went to outlet to buy gifts for back to country trip in a week or so.
Night: Saw the post about DCA treatment. Searched google and found wiki description. Seems to be a paper on cancer cell in 2007. Talking about mitochondria induced apoptosis can be restored by DCA in cancer. Haven’t read the paper, don’t know if it’s restore MT priming or help with MT integrity or something else. Also don’t know if it works with P53 loss or LKB loss, particularly if MT priming proteins are missing. Got陈津生’s recipe, seems to be focusing on lung and stomach plus some liver， together with半枝蓮。
2010/10/17 Sun. Daytime: work and sleep.
Night: called SHR just now, parents are going to see him first. Thought about chineses medicine and cancer, and comes up an analogy for it. In case of flooding, we should try to find the cause for it. It could be that we don’t enough forest upstream, or it rained too much upstream. We also have concern about downstream so that it won’t overflow and gets everywhere flooded. Chinese medicine is good at finding causes and planting trees upstream, is good at building damps downstream to fight flooding. Yet, the already formed flood is still there, and we need to find a way to get rid of it. No matter targeting therapy, chemotherapy or surgery are all fast ways of remove the “flood”. There are also ways in chinese medicine to dispose the “flood”, but few doctors are good at using it. Let’s imagine in ancient times, people usually don’t live that long (because there were not so many doctors around and there were no high quality public hygiene), plus pollution was much much less than today, therefore few cancer patients were there for doctors to practice and find best ways to deal with them. Anyway, if use small cell lung cancer as example. We all know that Chinese medicine is not very good at treating small cell. Why? Because small cell generally has p53 loss and progress really fast. This is like a huge flood coming along, and the damp built by Chinese medicine is not enough to stop the flooding. Even you already stop the sources, the flood is already there, and it’s too late. There should be a way that Chinese medicine can also deal with the flood itself. Along with these notions, we shouldn’t disregard western medicine as 倪海夏are doing, because we can take western medicine into Chinese medicine, just consider them as 甘草or 半枝莲. Let’s say chemo drugs have certain symptoms on patients (side effects and so on). We should be able to have some idea about its 药性, and use that in conjunction with Chinese medicine for best results.
Parents called back, SHR said it looks like adeno. He said the mediastinal nodes are too small to do biopsy, and it’s not advanced enough to use Mediastinoscopy for that in China. So, we have to go for the primary. Called HXH, got voicemail. Emailed him to confirm about tissue fixation and embedding. Plan to go back next week. Need to get ticket tomorrow. Start to read DCA cancer cell paper. Thought: try DCA plus AZD and chemo for kras/LKB
They came back from hospital. Have to wait for bed. Sounds like it is still surgery suitable. Well, we’ll see how it goes. Found short msg in qiji system. Got a QQ number. Register and ask to join. Got response for the mod. |
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