这个新闻谁看过，有人做过这个治疗吗？
美国特效抗肿瘤产品U.S.Ｇenistein分子弹在我国上市时间: 2009-2-16 来源:美国分子弹抗癌制剂最新快讯:中国医学科学院近日宣布，经该院多方努力,由世界权威肿瘤研究机构美国国立肿瘤研究中心(NCI)研制开发的全新高效抗肿瘤制剂美国Genistein分子弹,将于近日登陆中国。
日前，笔者参加了由美国国立肿瘤研究中心（NCI）和中国医学科学院共同举办的Genistein分子弹合作签约仪式。据中方引进单位——中国医学科学院李荣立教授介绍：其实从得知美国国立肿瘤研究中心(NCI)研制成功Genistein分子弹伊始，中国医学科学院就开始了漫长的引进历程。为此，中国医学科学院在七年间曾派员赴美二十多次，并积极申请加入Genistein分子弹全球临床验证工作，经过多方努力，才于近日获准正式引进。
Genistein分子弹为何会得到中国医学科学院这个我国最高级别的医学科研机构如此高度的重视，并使众多肿瘤专家投入此中乐此不疲呢？
美国国立肿瘤研究中心主任CLARL.BOB克拉尔·鲍勃称：“Genistein分子弹是全球肿瘤研究权威机构——美国国立肿瘤研究中心（NCI）历时数年的研究成果，它不仅是凝聚了两项诺贝尔奖转化成果的高科技产物。更令人惊叹的是，它还是目前全球惟一具有明确分子式、机理清楚、抗肿瘤性强的智能靶基因制剂。
Genistein分子弹独有的智能靶基因技术，不仅可彻底敲除肿瘤细胞，而且还可有效防止肿瘤的复发、转移，提高机体自身免疫力，达到治养结合的惊人功效。据美国国立肿瘤研究中心、日本大阪肿瘤研究中心、中国医学科学院等五大权威肿瘤机构提供的临床验证报告显示：Genistein分子弹单独使用，能快速抑制肿瘤细胞DNA、RNA的合成，有效控制瘤体增长，防止肿瘤的复发和转移，使肿瘤自然缩小、消失；配合放、化疗使用，可起到叠加协同的作用，提高抗肿瘤效果，并减轻放、化疗的毒副作用。同时最大程度的减少患者在治疗过程中出现恶心、呕吐、消瘦、脱发等各种痛苦，减缓白细胞急速降低，恢复血象正常值。从而延长肿瘤患者生存时间，提高患者生存质量。
Genistein分子弹的成功问世不仅引起中国医学科学院的关注，全球其它国家肿瘤研究机构也同时都在密切关注并为引进而积极行动。
发布会还特别邀请中国临床实验区的康复患者李毅雄出席：8年前他曾被诊断为晚期肺部肿瘤，8年过去了，当初被判“死刑”的他，如今仍然很好的活着！在发布会现场李毅雄激动地热泪盈眶：“八年了，连自己都没想到，还能活到今天！”而在欧美各国，Genistein分子弹早已让更多肿瘤患者受益，很多人都像李毅雄一样，不但活着，而且活得健康快乐！
留美博士、中国医学科学院专家李勇波告诉笔者：“我们医学科学院一直以引进、研究国外先进医疗技术作为一项重要工作，以Genistein分子弹为代表的先进抗肿瘤基因制剂无疑是世界肿瘤治疗领域的革命性突破。大量数据显示Genistein在世界其他地区已经取得了相当大的成功，此次终于能顺利引进，无论是对我们中国医学科学院，还是对广大的肿瘤患者来说，都是一件令人振奋的消息。” Genistein (酪氨酸蛋白激酶抑制剂)
产品编号 产品名称 包装
S1628 Genistein (酪氨酸蛋白激酶抑制剂) 25mg
产品简介：
􀂾 Genistein是一种常用的酪氨酸蛋白激酶抑制剂。Genistein可以通透细胞，抑制酪氨酸蛋白激酶(tyrosine proteinkinase)，抑制许多蛋白的酪氨酸磷酸化。
􀂾 Genistein分子量为270.24，分子式为C15H10O5，CAS Number：446-72-0。本产品纯度大于98%。
􀂾 本Genistein为进口分装，可溶解于DMSO。
包装清单：
产品编号 产品名称 包装
S1628 Genistein (酪氨酸蛋白激酶抑制剂) 25mg
— 说明书 1份
保存条件：
4℃避光保存，一年有效。-20℃避光保存，至少两年有效。
注意事项：
􀂾 Genistein可能对人体有害，请注意适当防护。
􀂾 为了您的安全和健康，请穿实验服并戴一次性手套操作。
使用说明：
1. Genistein常见使用浓度范围为1-100μM。具体的最佳工作浓度请参考相关文献，或根据实验目的，以及所培养的特定细胞和组织，通过实验进行摸索和优化。 我也看到了，但不知“分子弹”是否真的这么有效？！为什么它不是通过医院给病人用呢？有人知道吗？ 同问，很想知道具体的相关信息，谢谢大家了 顶一下，希望有人能发布更详细的信息， 是从大豆和豆腐以及一些植物中提炼出来的物质，没有查到FDA批准书，好像是保健食品
Genistein
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Genistein
IUPAC name
5,7-Dihydroxy-3-(4-hydroxyphenyl)chromen-4-one
Other names 4',5,7-Trihydroxyisoflavone
Identifiers
CAS number
PubChem 5280961
SMILES
C1=CC(=CC=C1C2=COC3=CC(=CC(=C3C2=O)O)O)O
Properties
Molecular formula C15H10O5
Molar mass 270.24 g mol−1
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)
Infobox references
Genistein is one of several known isoflavones. Isoflavones, such as genistein and daidzein, are found in a number of plants, with soybeans and soy products like tofu and textured vegetable protein being the primary food source. Soy isoflavones are a group of compounds found in and isolated from the soybean. Besides functioning as antioxidants, many isoflavones have been shown to interact with animal and human estrogen receptors, causing effects in the body similar to those caused by the hormone estrogen. Soy isoflavones also produce non-hormonal effects.
Contents
* 1 Biological effects
o 1.1 Antioxidant
o 1.2 Atherosclerosis
o 1.3 Cancer links
o 1.4 Effects in males
* 2 Molecular function
* 3 Sources
* 4 References
Biological effects
Antioxidant
Some isoflavones act as antioxidants to counteract damaging effects of free radicals in tissues. Genistein has a converse effect in this area compared to other isoflavones; It stimulates a step in nitrate synthesis, which is oxidation.
Atherosclerosis
Genistein protects against pro-inflammatory factor-induced vascular endothelial barrier dysfunction and inhibits leukocyte-endothelium interaction, thereby modulating vascular inflammation, a major event in the pathogenesis of atherosclerosis.
Cancer links
Some isoflavones have been found to have antiangiogenic effects (blocking formation of new blood vessels), and may block the uncontrolled cell growth associated with cancer, most likely by inhibiting the activity of substances in the body that regulate cell division and cell survival (growth factors). However, Genistein has the effect of promoting breast cancer in one study.
Studies show that gastrointestinal cancer occurs less frequently among North Americans who do not learn to eat meat. North Americans who go to other continents without learning to eat vegetables show more digestive tract cancer than neighbours.
Timing of phytoestrogen use is important.
Genistein makes some cells more sensitive to radio-therapy.
Though research is still ongoing, some recent studies have indicated that soy's phytoestrogens could be contributive factors in some forms of breast cancer, penile birth defects, and infantile leukemia.
Some studies have raised the concern that genistein might increase the risk of leukemia, because it inhibits the enzyme topoisomerase which results in double strand DNA breaks, which are, in turn, mutagenic. Some cancer patients whose chemotherapy drugs inhibited topoisomerase later developed leukemia. An animal study suggested that GEN may not be safe for postmenopausal women with estrogen-dependent breast cancer.
Regardless, soy's phytoestrogens, or isoflavones, have been definitely shown to depress thyroid function and to cause infertility in every animal species studied so far.
Genistein's chief method of activity is as a tyrosine kinase inhibitor. Tyrosine kinases are less widespread than their ser/thr counterparts but implicated in almost all cell growth and proliferation signal cascades. Genistein has been used to selectively target pre B-cells via conjugation with an antibody. This highly successful study in mice has promising benefits for future chemotherapy
Effects in males
Isoflavones can act like estrogen, stimulating development and maintenance of female characteristics or they can block cells from using cousins of estrogen. In vitro studies have proven genistein to induce apoptosis of testicular cells at certain levels, thus raising concerns about effects it could have on male fertility.
Molecular function
Genistein influences several targets in living cells. One important function is the inhibition of several tyrosine kinases. Genistein also inhibits the mammalian hexose transporter GLUT1 and contraction of several types of smooth muscles. Genistein can bind to the CFTR channel, potentiating its opening at low concentration and inhibiting it a higher doses.
Sources
Concentrations of genistein in Pueraria mirifica (White Kawo Krua) are so close to zero that experimental estimates of error equalled concentration measured.
搜索了下国内关于genistein的情况
产 品 介 绍享誉国际抗癌领域的最新智能靶基因制剂——分子弹
产品说明：
Product Description：
本品是以天然异黄酮提取物为原料，采用先进技术开发生产的 胶囊类产品，其主要成分是genistein，经功能试验证实，该产品能辅助抑制肿瘤的生长转移。
This product is capsule product developed and produced with advanced technology, using natural isoflavone extract as raw material. Its essential component is genistein . The function test confirmed that this product can inhibit the growth and metastasis of the tumor.
英文名：genistein
English Name: genistein
主要原料：异黄酮提取物
Principal Raw Material: isoflavone extract
功效成分及含量：每一百毫克含：genistein14—18毫克
Function Elements and Contents: genistein 14—18 mg/100mg
功能：辅助抑制肿瘤
Function: assisting inhibit tumor
适宜人群：各种肿瘤患者
Appropriate Crowd: patients suffering various kinds of tumors >
服用方法及服用量：每三个月为一个服用周期，每日3次，每次3粒，饭后温开水送服
Usage and Dosage: One taking period isthree months. Three times a day, three tablets one time, take it mixing with warm water after dinner.
规格：250毫克×50粒×3瓶/盒
Specification: 250 mg* 50grain*3 bottles/box
保质期：18个月
Guarantee Period: 18 months
储存方法：置于阴凉干燥处
Storage Method: kept in cool and dry place
批号及生产日期：见外包装
Batch Number and Manufacture Date: see outer packing
研究引进：中国医学科学院
Introduced Research: Chinese Academy of Medical Sciences
出品单位：中美合资霹克医药科技有限公司/ 荣立药物研究所
Presenting Units: Sino-American Joint Venture Peak Pharmaceutical Technology Co., Ltd./ Rongli Pharmacology Institute
地址：石家庄市新石北路368号高新技术产业开发区海外留学人员创业园
Address: No.368, The Overseas Students Pioneer Park, High-tech Industrial Development Zone, Xin Shi North Road, Shijiazhuang City
网址：www.fzdcancer.com
Website:www.fzdcancer.com
到底效果如何啊?有人用过吗
有人用过这个药吗?????
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